Discospondylityis
- Cefalexin
- Amoxicillin/clavulanate
- Trimethoprim/sulfadiazine
- Clindamycin
Intravenously, if severe neurological compromise or signs of sepsis
Treat for minimum 6–8 weeks (based on clinical response)
Bacterial Infective (Septic) Arthritis:
- Cefalexin
- Amoxicillin/clavulanate
Treat for 4 weeks OR until synovial fluid neutrophils <3%
Osteomyelitis
- Cefalexin OR cefuroxime
- Amoxicillin/clavulanate
Intravenously for first 2–3 days then orally for 6–8 weeks
